Oxycodone and acetaminophen tablets expose patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing oxycodone and acetaminophen tablets, and monitor all patients regularly for the development of these behaviors and conditions [see WARNINGS]. Oxycodone and acetaminophen tablets are used to manage pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate, and when other pain treatments such as non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Includes side effects, dosage, and more. Oxycodone and acetaminophen combination can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong opioid pain medicines. FDA Structured Product Label (SPL) for Oxycodone/apap (NDC 61919-432). Review professional prescribing information, including boxed warning, description, Detailed Acetaminophen / Oxycodone dosage information for adults. Includes dosages for Pain; plus renal, liver and dialysis adjustments. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Oxycodone/acetaminophen has a risk for abuse and addiction, which can lead to overdose and death. Oxycodone/acetaminophen may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should have you take the smallest dose of oxycodone/acetaminophen that works, and take it for the shortest possible time. See also How to Use section for more information about. Oxycodone (Roxicodone, OxyContin) and oxycodone / acetaminophen (Percocet) are opioid medications. They're FDA approved to treat severe pain that can’t be relieved by non-opioid medications. Like all opioids, they’re classified as controlled substances because of their risk for dependence, misuse, and overdose. When comparing oxycodone versus Percocet, there are a few things to consider. Indications Oxycodone and Acetaminophen Tablets are indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration and persist over the course of therapy, reserve opioid analgesics, including. Oxycodone is a semisynthetic pure opioid agonist whose principal therapeutic action is analgesia. Other pharmacological effects of oxycodone include anxiolysis, euphoria and feelings of relaxation. These effects are mediated by receptors (notably μ and κ) in the central nervous system for endogenous opioid-like compounds such as endorphins and enkephalins. Oxycodone produces respiratory.